2407405 - Disclosure - (Accounts Payable and Accrued Expenses) (Details) link:presentationLink link:calculationLink link:definitionLink 2108100 - Disclosure - Business Combinations link:presentationLink link:calculationLink link:definitionLink 2408404 - Disclosure - Business Combinations Pro forma information (Details) link:presentationLink link:calculationLink link:definitionLink 2308301 - Disclosure - Business Combinations (Tables) link:presentationLink link:calculationLink link:definitionLink 2116100 - Disclosure - Commitments and Contingencies link:presentationLink link:calculationLink link:definitionLink 2416402 - Disclosure - Commitments and Contingencies (Details) link:presentationLink link:calculationLink link:definitionLink 1002000 - Statement - Consolidated Balance Sheets link:presentationLink link:calculationLink link:definitionLink 1002501 - Statement - Consolidated Balance Sheets (Parenthetical) link:presentationLink link:calculationLink link:definitionLink 1006000 - Statement - Consolidated Statement of Cash Flows link:presentationLink link:calculationLink link:definitionLink 1004000 - Statement - Consolidated Statements of Comprehensive Loss link:presentationLink link:calculationLink link:definitionLink 1003000 - Statement - Consolidated Statements of Operations link:presentationLink link:calculationLink link:definitionLink 1005000 - Statement - Consolidated Statements of Stockholders' Equity link:presentationLink link:calculationLink link:definitionLink 0001000 - Document - Document and Entity Information link:presentationLink link:calculationLink link:definitionLink 2106100 - Disclosure - Fair Value Measurements link:presentationLink link:calculationLink link:definitionLink 2406403 - Disclosure - Fair Value Measurements (Change in Fair Value) (Details) link:presentationLink link:calculationLink link:definitionLink 2406404 - Disclosure - Fair Value Measurements Change In Fair Value Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 2406402 - Disclosure - Fair Value Measurements (Financial Instruments) (Details) link:presentationLink link:calculationLink link:definitionLink 2406406 - Disclosure - Fair Value Measurements (Narrative) (Details) link:presentationLink link:calculationLink link:definitionLink 2306301 - Disclosure - Fair Value Measurements (Tables) link:presentationLink link:calculationLink link:definitionLink 2113100 - Disclosure - Income Taxes link:presentationLink link:calculationLink link:definitionLink 2413401 - Disclosure - Income Taxes (Narrative) (Details) link:presentationLink link:calculationLink link:definitionLink 2109100 - Disclosure - Intangible Assets link:presentationLink link:calculationLink link:definitionLink 2409403 - Disclosure - Intangible Assets (Finite-Lived Intangible Assets) (Details) link:presentationLink link:calculationLink link:definitionLink 2409405 - Disclosure - Intangible Assets (Finite-Lived Intangible Assets, Future Amortization Expense) (Details) link:presentationLink link:calculationLink link:definitionLink 2409402 - Disclosure - Intangible Assets (Intangible Assets Useful Lives) (Details) link:presentationLink link:calculationLink link:definitionLink 2409404 - Disclosure - Intangible Assets (Narrative) (Details) link:presentationLink link:calculationLink link:definitionLink 2309301 - Disclosure - Intangible Assets (Tables) link:presentationLink link:calculationLink link:definitionLink 2103100 - Disclosure - Net Loss Per Share link:presentationLink link:calculationLink link:definitionLink 2403402 - Disclosure - Net Loss Per Share (Details) link:presentationLink link:calculationLink link:definitionLink 2403403 - Disclosure - Net Loss Per Share (Narrative) (Details) link:presentationLink link:calculationLink link:definitionLink 2303301 - Disclosure - Net Loss Per Share (Tables) link:presentationLink link:calculationLink link:definitionLink 2102100 - Disclosure - Organization and Summary of Significant Accounting Policies link:presentationLink link:calculationLink link:definitionLink 2202201 - Disclosure - Organization and Summary of Significant Accounting Policies (Policies) link:presentationLink link:calculationLink link:definitionLink 2107100 - Disclosure - Other Balance Sheet Amounts link:presentationLink link:calculationLink link:definitionLink 2407403 - Disclosure - Other Balance Sheet Amounts (Amortized cost and Fair Value of Marketable Securities) (Details) link:presentationLink link:calculationLink link:definitionLink 2407402 - Disclosure - Other Balance Sheet Amounts (Investments in Marketable Securities) (Details) link:presentationLink link:calculationLink link:definitionLink 2407404 - Disclosure - Other Balance Sheet Amounts (Narrative) (Details) link:presentationLink link:calculationLink link:definitionLink 2307301 - Disclosure - Other Balance Sheet Amounts (Tables) link:presentationLink link:calculationLink link:definitionLink 2112100 - Disclosure - Stock-Based Compensation link:presentationLink link:calculationLink link:definitionLink 2412402 - Disclosure - Stock-Based Compensation (Details) link:presentationLink link:calculationLink link:definitionLink 2412410 - Disclosure - Stock-Based Compensation (Employee Stock Purchase Plan Narrative) (Details) link:presentationLink link:calculationLink link:definitionLink 2412411 - Disclosure - Stock-Based Compensation (Expense) (Details) link:presentationLink link:calculationLink link:definitionLink 2412406 - Disclosure - Stock-Based Compensation (Restricted Stock Activity) (Details) link:presentationLink link:calculationLink link:definitionLink 2412407 - Disclosure - Stock-Based Compensation (Restricted Stock Narrative) (Details) link:presentationLink link:calculationLink link:definitionLink 2412408 - Disclosure - Stock-Based Compensation (Restricted Stock Units Activity) (Details) link:presentationLink link:calculationLink link:definitionLink 2412409 - Disclosure - Stock-Based Compensation (Restricted Stock Units Narrative) (Details) link:presentationLink link:calculationLink link:definitionLink 2412404 - Disclosure - Stock-Based Compensation (Stock Options Narrative) (Details) link:presentationLink link:calculationLink link:definitionLink 2412403 - Disclosure - Stock-Based Compensation (Stock Options Outstanding) (Details) link:presentationLink link:calculationLink link:definitionLink 2312301 - Disclosure - Stock-Based Compensation (Tables) link:presentationLink link:calculationLink link:definitionLink 2412405 - Disclosure - Stock-Based Compensation (Valuation Assumptions) (Details) link:presentationLink link:calculationLink link:definitionLink 2118100 - Disclosure - Subsequent Event link:presentationLink link:calculationLink link:definitionLink 2418401 - Disclosure - Subsequent Event (Details) link:presentationLink link:calculationLink link:definitionLink